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Publications

Preprints

Peer Reviewed

  1. Orlando KA, Douglas AK, Abudu A, Wang Y, Tessier-Cloutier B, Su W, Peters A, Sherman LS, Moore R, Nguyen V, Negri GL, Colborne S, Morin GB, Kommoss F, Lang JD, Hendricks WP, Raupach EA, Pirrotte P, Huntsman DG, Trent JM, Parker JS, Raab JR*, Weissman BE. 2020*. Re-expression of SMARCA4/BRG1 in small cell carcinoma of ovary, hypercalcemic type (SCCOHT) promotes an epithelial-like gene signature through an AP-1-dependent mechanism. Elife 9. doi:10.7554/eLife.59073   co-corresponding
  2. Tulasi DY, Castaneda DM, Wager K, Hogan CB, Alcedo KP, Raab JR, Gracz AD. 2021. Sox9EGFP Defines Biliary Epithelial Heterogeneity Downstream of Yap Activity. Cell Mol Gastroenterol Hepatol 11:1437–1462. doi:10.1016/j.jcmgh.2021.01.009
  3. Raab JR, Tulasi DY, Wager KE, Morowitz JM, Magness ST, Gracz AD. Quantitative classification of chromatin dynamics reveals regulators of intestinal stem cell differentiation. Development. 2019. doi:10.1242/dev.181966
  4. Orlando KA, Nguyen V, Raab JR, Walhart T, Weissman BE. Remodeling the cancer epigenome: mutations in the SWI/SNF complex offer new therapeutic opportunities. Expert Rev Anticancer Ther. 2019; doi:10.1080/14737140.2019.1605905
  5. Raab JR, Smith KN, Spear CC, Manner CJ, Calabrese JM, Magnuson T. SWI/SNF remains localized to chromatin in the presence of SCHLAP1. Nature Genetics. 2019 Jan;51(1):26-29 doi: 10.1101/322065
  6. Runge JS*, Raab JR*, Magnuson T. Identification of Two Distinct Classes of the Human INO80 Complex Genome-Wide. G3: Genes, Genomes, Genetics; 2018;8: 1095–1102. doi:10.1534/g3.117.300504
  7. Gracz AD, Samsa LA, Fordham MJ, Trotier DC, Zwarycz B, Lo Y-H, et al. SOX4 Promotes ATOH1-independent Intestinal Secretory Differentiation Toward Tuft and Enteroendocrine Fates. Gastroenterology. Elsevier; 2018; doi:10.1053/j.gastro.2018.07.023
  8. Raab JR, Runge JS, Spear CC, Magnuson T. Co-regulation of transcription by BRG1 and BRM, two mutually exclusive SWI/SNF ATPase subunits. Epigenetics Chromatin. 2017;10: 62. doi:10.1186/s13072-017-0167-8
  9. Runge JS, Raab JR, Magnuson T. Epigenetic Regulation by ATP-Dependent Chromatin-Remodeling Enzymes: SNF-ing Out Crosstalk. Curr Top Dev Biol. 2016;117: 1–13. doi:10.1016/bs.ctdb.2015.10.009
  10. Raab JR, Resnick S, Magnuson T. Genome-Wide Transcriptional Regulation Mediated by Biochemically Distinct SWI/SNF Complexes. PLoS Genet. 2015;11: e1005748. doi:10.1371/journal.pgen.1005748
  11. Chandler RL, Raab JR, Vernon M, Magnuson T, Schisler JC. Global gene expression profiling of a mouse model of ovarian clear cell carcinoma caused by ARID1A and PIK3CA mutations implicates a role for inflammatory cytokine signaling. Genom Data. 2015;5: 329–332. doi:10.1016/j.gdata.2015.06.027
  12. Rothbart SB, Dickson BM, Raab JR, Grzybowski AT, Krajewski K, Guo AH, et al. An Interactive Database for the Assessment of Histone Antibody Specificity. Mol Cell. Elsevier; 2015;59: 502–511. doi:10.1016/j.molcel.2015.06.022
  13. Chandler RL, Damrauer JS, Raab JR, Schisler JC, Wilkerson MD, Didion JP, et al. Coexistent ARID1A-PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling. Nat Commun. Nature Publishing Group; 2015;6: 6118. doi:10.1038/ncomms7118
  14. Kirkland JG, Raab JR, Kamakaka RT. TFIIIC bound DNA elements in nuclear organization and insulation. Biochim Biophys Acta. Elsevier; 2013;1829: 418–424. doi:10.1016/j.bbagrm.2012.09.006
  15. Raab JR, Chiu J, Zhu J, Katzman S, Kurukuti S, Wade PA, et al. Human tRNA genes function as chromatin insulators. EMBO J. John Wiley & Sons, Ltd; 2012;31: 330–350. doi:10.1038/emboj.2011.406
  16. Raab JR, Kamakaka RT. Insulators and promoters: closer than we think. Nat Rev Genet. Nature Publishing Group; 2010;11: 439–446. doi:10.1038/nrg2765
  17. Dhillon N, Raab J, Guzzo J, Szyjka SJ, Gangadharan S, Aparicio OM, et al. DNA polymerase epsilon, acetylases and remodelers cooperate to form a specialized chromatin structure at a tRNA insulator. EMBO J. 2009;28: 2583–2600. doi:10.1038/emboj.2009.198
  18. Chaudhry UI, Plitas G, Burt BM, Kingham TP, Raab JR, DeMatteo RP. NK dendritic cells expanded in IL-15 exhibit antitumor responses in vivo. J Immunol. American Association of Immunologists; 2007;179: 4654–4660. Available: http://www.ncbi.nlm.nih.gov/pubmed/17878363
  19. Plitas G, Chaudhry UI, Kingham TP, Raab JR, DeMatteo RP. NK dendritic cells are innate immune responders to Listeria monocytogenes infection. J Immunol. American Association of Immunologists; 2007;178: 4411–4416. Available: http://www.ncbi.nlm.nih.gov/pubmed/17371998
  20. Kingham TP, Chaudhry UI, Plitas G, Katz SC, Raab J, DeMatteo RP. Murine liver plasmacytoid dendritic cells become potent immunostimulatory cells after Flt-3 ligand expansion. Hepatology. Wiley Subscription Services, Inc., A Wiley Company; 2007;45: 445–454. doi:10.1002/hep.21457
  21. Chaudhry UI, Kingham TP, Plitas G, Katz SC, Raab JR, DeMatteo RP. Combined stimulation with interleukin-18 and CpG induces murine natural killer dendritic cells to produce IFN-gamma and inhibit tumor growth. Cancer Res. American Association for Cancer Research; 2006;66: 10497–10504. doi:10.1158/0008-5472.CAN-06-1908
  22. Bleier JI, Katz SC, Chaudhry UI, Pillarisetty VG, Kingham TP 3rd, Shah AB, et al. Biliary obstruction selectively expands and activates liver myeloid dendritic cells. J Immunol. American Association of Immunologists; 2006;176: 7189–7195. Available: http://www.ncbi.nlm.nih.gov/pubmed/16751362
  23. Chaudhry UI, Katz SC, Kingham TP, Pillarisetty VG, Raab JR, Shah AB, et al. In vivo overexpression of Flt3 ligand expands and activates murine spleen natural killer dendritic cells. FASEB J. FASEB; 2006;20: 982–984. doi:10.1096/fj.05-5411fje
  24. Katz S, Kingham TP, Chaudhry U, Raab J, DeMatteo RP. GM-CSF expands and activates Kupffer cells in vivo. HEPATOLOGY. JOHN WILEY & SONS INC 111 RIVER ST, HOBOKEN, NJ 07030 USA; 2006. p. 572A–573A.
  25. Chaudhry U, Kingham P, Plitas G, Katz S, Stabelford J, Raab J, et al. Interleukin-18 and the toll-like receptor 9 ligand CpG stimulate murine splenic natural killer dendritic cells (NKDC) to proliferate and secrete IFN-gamma. J Am Coll Surg. Elsevier; 2006;203: S79–S80.
  26. Bembenek J, Kang J, Kurischko C, Li B, Raab JR, Belanger KD, et al. Crm1-mediated nuclear export of Cdc14 is required for the completion of cytokinesis in budding yeast. Cell Cycle. Taylor & Francis; 2005;4: 961–971. Available: http://www.ncbi.nlm.nih.gov/pubmed/15917648

Raab Lab

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Chapel Hill NC, 25799